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Human IL23A/p19 Neutralizing Antibody

Human IL23A/p19 Neutralizing Antibody

Item no.	CT035-M066-500
Manufacturer	Sino Biological
Amount	500 ug
Quantity options	200 ug 500 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Clone	M066
Specific against	other
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	sino
Available
Manufacturer - Category	Antibody
Antigen molecule name	IL23
Storage	This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Immunogen	Recombinant Human IL23A & Mouse IL12B Heterodimer Protein (Catalog#CT035-A99H)
Purification	Protein A
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human IL23A & Mouse IL12B Heterodimer (rh Human IL23A & Mouse IL12B Heterodimer; Catalog#CT035-A99H; Q9NPF7 & P43432; Met1-Pro189 & Met1-Ser335) and was produced using recombinant antibody technology.
Specificity	Human IL23A & Human IL12B Heterodimer
Cross reactivity	Has cross-reactivity with Cynomolgus IL-23 (IL12B & IL23A Heterodimer) and Human IL-23 (IL12B & IL23A Heterodimer) Protein in ELISA assay
No cross-reactivity	No cross-reactivity with Mouse IL-23 (IL12B & IL23A Heterodimer) and Rat IL-23 (IL12B & IL23A Heterodimer) Protein in ELISA assay
Endotoxin	< 2.91 EU/mg
Buffer	0.2 um filtered solution in Histidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0
Block	This antibody can block the binding of recombinant human IL23 Protein (CT048-H08H) to its recombinant receptor IL23R (13840-H02H).
Neutralization	The neutralization activity of antibody is Measured by its ability to neutralize IL23induced IL17A secretion in mouse splenocytes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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