Comparison

Recombinant Canine ALK-1 Protein (hFc Tag) European Partner

Item no. 70049-D02H-200
Manufacturer Sino Biological
Amount 200 ug
Quantity options 1 mg 2 mg 200 ug 4 mg
Category
Type Proteins
Format Human Cell
Specific against Dog (Canine, Canis lupus familiaris)
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 70049-D02H
Similar products ACVRL1
Available
Manufacturer - Category
Protein
Molecule
ACVRL1
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the canine ACVRL1(E2R174) (Met1-Gln119) was expressed with the Fc region of human IgG1 at the C-terminus.
Expressed Host
Human Cells
Purity
> 95 % as determined by SDS-PAGE
Bio-Activity
Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells.
The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombinant human BMP-9.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Gly 22
Molecule Mass
The recombinant canine ACVRL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 339 amino acids and has a predicted molecular mass of 37.9 kDa. The apparent molecular mass of the protein is approximately 43-47 kDa in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Accession
E2R174
Amino acid sequence
Met1-Gln119
TAG
C-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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