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Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)

Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)

Manufacturer	Sino Biological
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Amount	100ug
Item no.	10041-H03H-100
eClass 6.1	34160400
eClass 9.0	42020190
Available
Molecule	TNFRSF9
Synonym	4-1BB, CD137, CDw137, ILA
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the N-terminal fragment (Met 1-Gln 186) of the extracellular domain of human 4-1BB (NP_001552.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 95 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . Immobilized recombinant mouse 4-1BB Ligand at 20 ug/ml (100 ul/well) can bind human 4-1BB with a linear range of 15.6-500 ng/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Gln 25
Molecule Mass	The recombinant human 4-1BB/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 409 amino acids and has a calculated molecular mass of 45.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh4-1BB/Fc monomer is approximately 60-65 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_001552.2
Amino acid sequence	Met1-Gln186
TAG	C-human IgG1-Fc & His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 5/30/2024