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Recombinant Human PD-L1/B7-H1 Protein (ECD, mFc Tag), HPLC-verified

Recombinant Human PD-L1/B7-H1 Protein (ECD, mFc Tag), HPLC-verified

Item no.	10084-H05H-100
Manufacturer	Sino Biological
Amount	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Myelofibrosis Mesothelioma
Type	Proteins
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B7-H, B7-H1, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Available
Manufacturer - Category	Protein
Molecule	CD274
Synonym	B7-H, B7-H1, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the human CD274 (NP_054862.1) (Met1-Thr239) was expressed with the Fc region of mouse IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 95 % as determined by SDS-PAGE.
Bio-Activity	Measured by its ability to inhibit anti-CD3 antibody induced IFNgamma secretion in human T lymphocytes. The ED50 for this effect is 2-10 ug/mL.
Endotoxin	< 1.0 EU per ug protein as determined by the LAL method.
Predicted N Terminal	Phe 19
Molecule Mass	The recombinant human CD274 consists of 455 amino acids and predicts a molecular mass of 51.7 kDa.
Formulation	Lyophilized from sterile PBS, pH 7.4.
Accession	NP_054862.1
Amino acid sequence	Met1-Thr239
TAG	C-mouse IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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