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Recombinant Human Erythropoietin R/EPOR Protein (hFc Tag)

Recombinant Human Erythropoietin R/EPOR Protein (hFc Tag)

Item no.	10707-H02H-100
Manufacturer	Sino Biological
Amount	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg 50 ug
Category	Oncology By Cell Type Hematology Leukemia Lymphoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Conjugate/Tag	Fc
Purity	> 90 % as determined by SDS-PAGE
Sequence	Met1-Pro250
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EPO-R
Similar products	EPOR
Available
Manufacturer - Type	Protein
Manufacturer - Conjugate / Tag	C-human IgG1-Fc
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	EPOR
Protein Construction	A DNA sequence encoding the extracellular domain (Met-Pro 250) of human erythropoietin receptor (NP_000112.1) precursor was expressed with the C-terminal fused Fc region of human IgG1.
Expressed Host	Human Cells
Bio-Activity	1. Measured by its binding ability in a functional ELISA. Immobilized CD131 at 10 ug/ml (100 ul/well) can bind biotinylated recombinant human EPOR with a linear range of 0.16-4 ug/ml. 2. Measured by its ability to inhibit EPO-dependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 4-16 ng/mL in the presence of 0.1 U/mL Recombinant Human EPO.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Ala 25
Molecule Mass	The recombinant human EPOR/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 460 amino acids and has a predicted molecular mass of 51.0 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEPOR/Fc monomer is approximately 55-60 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, 8% sucrose, 0.5% Tween-20, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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10707-H02H-100-datasheet.pdf

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Amount: 100 ug

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