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Recombinant Human IL-17RA Protein (ECD, His Tag), HPLC-verified

Recombinant Human IL-17RA Protein (ECD, His Tag), HPLC-verified

Item no.	10895-H08H-100
Manufacturer	Sino Biological
Amount	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg
Category	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Format	Human Cell
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R
Similar products	IL17RA
Available
Manufacturer - Category	Protein
Molecule	IL17RA
Synonym	CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain of human IL17RA (NP_055154.3) (Met 1-Trp 320) was fused with a polyhistidine tag at the C-terminus.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	1. Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL17A at 2 ug/ml (100 ul/well) can bind biotinylated human IL17RA with a linear range of 1.28-32 ng/ml. 2. Measured by its ability to inhibit IL-17-induced IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 0.03-0.12 ug/mL.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Leu 33
Molecule Mass	The recombinant human IL17RA consists of 299 amino acids and has a predicted molecular mass of 35 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL17RA is approximately 55-60 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_055154.3
Amino acid sequence	Met1-Trp320
TAG	C-His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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