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Recombinant Human IL-21 Receptor/IL-21R Protein (His Tag), HPLC-verified

Recombinant Human IL-21 Receptor/IL-21R Protein (His Tag), HPLC-verified

Item no.	11483-H08H-200
Manufacturer	Sino Biological
Amount	200 ug
Quantity options	1 mg 100 ug 2 mg 200 ug 4 mg
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Conjugate/Tag	HIS
Purity	> 92 % as determined by SDS-PAGE
Sequence	Met1-Pro236
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD360,NILR
Similar products	IL21R
Available
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	IL21R
Protein Construction	A DNA sequence encoding the human IL21R (Q9HBE5-1) extracellular domain (Met 1-Pro 236) was expressed, with a polyhistidine tag at the C-terminus.
Expressed Host	Human Cells
Bio-Activity	1. Measured by its ability to bind human IL-21 in a functional ELISA. 2. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 1-5 ng/ml in the presence of 10 ng/ml of recombinant human IL21. 3. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 50-200 pg/mL in the presence of 1 ng/ml of recombinant human IL21.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Cys 20
Molecule Mass	The recombinant human IL21R consists of 228 amino acids and predictes a molecular mass of 26.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL21R is approximately 42-46 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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