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Human NRG1-beta 1 Protein (ECD, Fc Tag)

Human NRG1-beta 1 Protein (ECD, Fc Tag)

Item no.	11609-H04H-50
Manufacturer	Sino Biological
Amount	50 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Melanoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Neuronal Cell Markers
Type	Proteins
Format	Human Cell
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Similar products	NRG1
Available
Molecule	NRG1
Synonym	ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the N-terminal fragment (Ser 2-Lys 246) of human NRG1 isoform beta1 (Q02297-6) was expressed, fused with the Fc region of mouse IgG1 at the N-terminus.
Expressed Host	Human Cells
Purity	> 88 % as determined by SDS-PAGE
Bio-Activity	1. Measured by its ability to bind with human ErbB4-His (Cat:10363-H08H) in a functional ELISA. 2. Measured by its ability to bind with human ErbB3-His (Cat:10201-H08H) in a functional ELISA.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Asp
Molecule Mass	The recombinant human NRG1/mFc is a disulfide-linked homodimer. The reduced monomer comprises 481 amino acids and has a predicted molecular mass of 53.4 kDa. The apparent molecular mass of the monomer is approximately 67 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	Q02297
Amino acid sequence	Ser2-Lys246
TAG	N-mouse IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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