Manufacturer |
Sino Biological
|
Category |
|
Type |
Proteins |
Specific against |
Human |
Format |
Human Cell |
Amount |
20ug |
Host |
Human |
Item no. |
11648-H08H-20 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Molecule |
JAG1 |
Synonym |
AGS, AHD, AWS, CD339, HJ1, Jagged 1, JAGL1 |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the human JAG1 (NP_000205.1) extracellular domain (Met 1-Ser 1046) was expressed, fused with a polyhistidine tag at the C-terminus. |
Expressed Host |
Human Cells |
Purity |
> 85 % as determined by SDS-PAGE |
Bio-Activity |
Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 4-20 ug/mL. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Gln 34 |
Molecule Mass |
The recombinant human JAG1 consists of 1024 amino acids and has a predicted molecular mass of 112 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh JAG1 is approximately 160-180 kDa due to glycosylation. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 |
Accession |
NP_000205.1 |
Amino acid sequence |
Met1-Ser1046 |
TAG |
C-His |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.