Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Bovine |
Isotype |
IgG |
Applications |
WB, ELISA |
Amount |
200ul |
Host |
Rabbit |
Item no. |
STJ98588-200 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
Q15382 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
RHEB is a protein encoded by the RHEB gene which is approximately 20, 5 kDa. RHEB is localised to the cytoplasm, Golgi apparatus membrane, cytosol and endoplasmic reticulum membrane. It is involved in the regulation of lipid metabolism, insulin signalling-generic cascades, mTOR signalling, RET signalling, AMP-activated protein kinase signalling and the phospholipase D signalling pathway. The RHEB gene is a member of the small GTPase superfamily and encodes the lipid-anchored, cell membrane protein, RHEB. This protein is vital in regulation of growth and cell cycle progression. RHEB is ubiquitous expressed with highest levels observed in skeletal and cardiac muscle. Mutations in the RHEB can result in tuberous sclerosis. STJ98588 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody binds to endogenous levels of RHEB. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from synthetic peptide derived from RHEB. |
Short Description |
Rabbit polyclonal against RHEB |
Tissue specificity |
Ubiquitous. Highest levels observed in skeletal and cardiac muscle. |
Cellular localization |
Endomembrane system Golgi apparatus membrane Cytoplasm, cytosol Endoplasmic reticulum membrane |
Dilution range |
WB 1:500-2000ELISA 1:10000-20000 |
Alternative names |
GTP-binding protein Rheb Ras homolog enriched in brain |
Protein name |
GTP-binding protein Rheb Ras homolog enriched in brain |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.