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Anti-MMACHC antibody

Anti-MMACHC antibody

Manufacturer	St John's Laboratory
Category	Food Safety Vitamines Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ112392-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q9Y4U1
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
Gene ID	25974
Gene symbol	MMACHC
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 63-282 of human MMACHC (NP_056321. 2).
Short Description	Rabbit polyclonal against MMACHC
Tissue specificity	Widely expressed. Expressed at higher level in fetal liver. Also expressed in spleen, lymph node, thymus and bone marrow. Weakly or not expressed in peripheral blood leukocytes.
Cellular localization	Cytoplasm
Molecular weight	Calculated: 31kDa. Observed: 32kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Methylmalonic Aciduria And Homocystinuria Type C Protein antibody Anti-Cblc antibody Anti-Cyanocobalamin Reductase antibody Anti-Cyanide-Eliminating antibody Anti-MMACHC antibody
Protein name	Methylmalonic Aciduria And Homocystinuria Type C Protein Cblc Cyanocobalamin Reductase Cyanide-Eliminating
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	MMAC_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 6/6/2024