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Anti-PKLR antibody

Anti-PKLR antibody

Manufacturer	St John's Laboratory
Category	Metabolism Glucose Homeostasis Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ114217-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P30613
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID	5313
Gene symbol	PKLR
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 446-556 of human PKLR (NP_000289. 1).
Short Description	Rabbit polyclonal against PKLR
Molecular weight	Calculated: 58kDa/61kDa. Observed: 62kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Pyruvate Kinase Pklr antibody Anti-Pyruvate Kinase 1 antibody Anti-Pyruvate Kinase Isozymes L/R antibody Anti-R-Type/L-Type Pyruvate Kinase antibody Anti-Red Cell/Liver Pyruvate Kinase antibody Anti-PKLR PK1 PKL antibody
Protein name	Pyruvate Kinase Pklr Pyruvate Kinase 1 Pyruvate Kinase Isozymes L/R R-Type/L-Type Pyruvate Kinase Red Cell/Liver Pyruvate Kinase
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	KPYR_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 5/23/2024