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Anti-SLC7A11 antibody

Anti-SLC7A11 antibody

Manufacturer	St John's Laboratory
Category	Oncology Antibodies By Cell Type Western Blot Cardiovascular Research Myocardial Infarction Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	STJ115640-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q9UPY5
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Gene ID	23657
Gene symbol	SLC7A11
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A11 (NP_055146. 1).
Short Description	Rabbit polyclonal against SLC7A11
Cellular localization	Membrane Multi-Pass Membrane Protein
Molecular weight	Calculated: 55kDa. Observed: 37kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Cystine/Glutamate Transporter antibody Anti-Amino Acid Transport System Xc-antibody Anti-Calcium Channel Blocker Resistance Protein Ccbr1 antibody Anti-Solute Carrier Family 7 Member 11 antibody Anti-Xct antibody Anti-SLC7A11 antibody
Protein name	Cystine/Glutamate Transporter Amino Acid Transport System Xc- Calcium Channel Blocker Resistance Protein Ccbr1 Solute Carrier Family 7 Member 11 Xct
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	XCT_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 5/23/2024