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Anti-GCSH antibody

Anti-GCSH antibody

Manufacturer	St John's Laboratory
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	STJ115650-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P23434
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Gene ID	2653
Gene symbol	GCSH
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human GCSH (NP_004474. 2).
Short Description	Rabbit polyclonal against GCSH
Cellular localization	Mitochondrion
Molecular weight	Calculated: 18kDa. Observed: 19kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Glycine Cleavage System H Protein-Mitochondrial antibody Anti-Lipoic Acid-Containing Protein antibody Anti-GCSH antibody
Protein name	Glycine Cleavage System H Protein-Mitochondrial Lipoic Acid-Containing Protein
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	GCSH_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 5/23/2024