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Anti-PLAU antibody

Anti-PLAU antibody

Manufacturer	St John's Laboratory
Category	Oncology Food Safety Proteins Antibodies Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Breast Cancer
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ25021-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P00749
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Gene ID	5328
Gene symbol	PLAU
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649. 1).
Short Description	Rabbit polyclonal against PLAU
Tissue specificity	Expressed in the prostate gland and prostate cancers.
Cellular localization	Secreted
Molecular weight	Calculated: 46kDa/48kDa. Observed: 49kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Urokinase-Type Plasminogen Activator antibody Anti-U-Plasminogen Activator antibody Anti-Upa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activator Chain B antibody Anti-PLAU antibody
Protein name	Urokinase-Type Plasminogen Activator U-Plasminogen Activator Upa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activator Chain B
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	UROK_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

available

Delivery expected until 5/23/2024