Anti-PLAT antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P00750

This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

PLAT

Rabbit polyclonal against PLAT

Secreted
Extracellular Space

WB 1:200-1:1000 IHC 1:50-1:200

Tissue-Type Plasminogen Activator
T-Pa
T-Plasminogen Activator
Tpa
Alteplase
Reteplase Cleaved Into-Tissue-Type Plasminogen Activator Chain A-Tissue-Type Plasminogen Activator Chain B

TPA_HUMAN