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Anti-TNFSF10 antibody (1-100)

Anti-TNFSF10 antibody (1-100)

Item no.	STJ114198-100
Manufacturer	St John's Laboratory
Amount	100 ul
Quantity options	100 ul 200 ul 50 ul
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Tumor Necrosis Factor Ligand Superfamily Member 10 antibody, Anti-Apo-2 Ligand antibody, Anti-Apo-2l antibody, Anti-Tnf-Related Apoptosis-Inducing Ligand antibody, Anti-Protein Trail antibody, Anti-Cd Antigen Cd253 antibody, Anti-TNFSF10 APO2L TRAIL antibody
Similar products	Anti-Tumor Necrosis Factor Ligand Superfamily Member 10 antibody Anti-Apo-2 Ligand antibody Anti-Apo-2l antibody Anti-Tnf-Related Apoptosis-Inducing Ligand antibody Anti-Protein Trail antibody Anti-Cd Antigen Cd253 antibody Anti-TN
Available
Storage Conditions	Store at-20°C and avoid freeze-thaw cycles.
Molecular Weight	Calculated: 11kDa/32kDa.
Description	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFSF10 (NP_003801. 1).
Tissue specificity	Widespread.most predominant in spleen, lung and prostate.
Cellular localization	Cell Membrane Single-Pass Type Ii Membrane Protein Secreted Exists Both As Membrane-Bound And Soluble Form
Clonality	Polyclonal
Protein name	Tumor Necrosis Factor Ligand Superfamily Member 10 Apo-2 Ligand Apo-2l Tnf-Related Apoptosis-Inducing Ligand Protein Trail Cd Antigen Cd253
Gene symbol	TNFSF10
Dilution range	WB 1:500-1:2000
Note	For Research Use Only (RUO).
Short Description	Rabbit polyclonal against TNFSF10

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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