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Anti-APOBEC3A antibody

Anti-APOBEC3A antibody

Manufacturer	St John's Laboratory
Category	Oncology Neuroscience Neuroinflammation Metabolism Antibodies By Cell Type Hematology Leukemia Sarcoma Obesity Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ114275-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P31941
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID	100913187
Gene symbol	APOBEC3A
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human APOBEC3A (NP_663745. 1).
Short Description	Rabbit polyclonal against APOBEC3A
Tissue specificity	Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia.
Cellular localization	Nucleus Cytoplasm
Molecular weight	Calculated: 21kDa/23kDa. Observed: 26kDa
Dilution range	WB 1:200-1:500
Alternative names	Anti-Dna Dc->Du-Editing Enzyme Apobec-3a antibody Anti-A3a antibody Anti-Phorbolin-1 antibody Anti-APOBEC3A antibody
Protein name	Dna Dc->Du-Editing Enzyme Apobec-3a A3a Phorbolin-1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	ABC3A_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

available

Delivery expected until 5/23/2024