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Busulfan

Busulfan

Item no.	TMO-T0923-1ml
Manufacturer	TargetMol
CASRN	55-98-1
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	CS(=O)(=O)OCCCCOS(C)(=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Myleran,Sulphabutin,Busulphan
Similar products	55-98-1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|DNA Alkylator/Crosslinker\|\|\|DNA Alkylation
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	246.3
Description	Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.
Pathways	Apoptosis\|\|\|DNA Damage/DNA Repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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