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Busulfan

Busulfan

Item no.	TMO-T0923-25mg
Manufacturer	TargetMol
CASRN	55-98-1
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9977
Citations	1. Meng A, et al. Y Res, 2003, 63(17), 5414-5419.
Smiles	CS(=O)(=O)OCCCCOS(C)(=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Myleran,Sulphabutin,Busulphan
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|DNA Alkylator/Crosslinker\|\|\|DNA Alkylation
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	246.3
Description	Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.
Pathways	Apoptosis\|\|\|DNA Damage/DNA Repair
Bioactivity	Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.
Receptor	DNA Alkylation

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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