Comparison

Doxorubicin hydrochloride European Partner

Item no. TMO-T1020-10mg
Manufacturer TargetMol
CASRN 25316-40-9
Amount 10 mg
Quantity options 1000 mg 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 25 mg 500 mg 50 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias NSC 123127,Hydroxydaunorubicin hydrochloride,Adriamycin HCl,DOX hydrochloride
Similar products 25316-40-9
Shipping Condition Cool pack
Available
Manufacturer - Targets
Autophagy|||HIV Protease|||Mitophagy|||AMPK|||ADC Cytotoxin|||HBV|||Apoptosis|||Topoisomerase|||Antibacterial|||Antibiotic
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
579.99
Description
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
Pathways
DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related|||Apoptosis|||Chromatin/Epigenetic|||Proteases/Proteasome|||Microbiology/Virology|||PI3K/Akt/mTOR signaling|||Autophagy
Formulate
C27H29NO11· HCl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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