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Trametinib

Trametinib

Item no.	TMO-T2125-10mg
Manufacturer	TargetMol
CASRN	871700-17-3
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 50 mg 5 mg
Category	Neuroscience Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	N(C1=C2C(N(C(=O)N(C2=O)C3CC3)C4=CC(NC(C)=O)=CC=C4)=C(C)C(=O)N1C)C5=C(F)C=C(I)C=C5
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	JTP-74057,GSK1120212
Similar products	871700-17-3
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|MEK\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	615.39
Description	Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.
Pathways	Apoptosis\|\|\|MAPK\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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