Comparison

Trametinib European Partner

Item no. TMO-T2125-10mM
Manufacturer TargetMol
CASRN 871700-17-3
Amount 1 mL x 10 mM (in DMSO)
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles N(C1=C2C(N(C(=O)N(C2=O)C3CC3)C4=CC(NC(C)=O)=CC=C4)=C(C)C(=O)N1C)C5=C(F)C=C(I)C=C5
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias JTP-74057,GSK1120212
Shipping Condition Cool pack
Available
Manufacturer - Targets
Apoptosis|||MEK|||Autophagy
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
615.39
Description
Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.
Pathways
Apoptosis|||MAPK|||Autophagy
Formulate
C26H23FIN5O4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL x 10 mM (in DMSO)
Available: In stock
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