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Cediranib

Cediranib

Manufacturer	TargetMol
Category	Oncology Neuroscience Neural Development Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Amount	100mg
Item no.	TMO-T2500-100mg
Targets	KIT
CASRN	288383-20-0
eClass 6.1	32169090
eClass 9.0	32169090
Available
Short Description	Cediranib (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit, selective more for VEGFR than PDGFR-α (36-fold), CSF-1R (110-fold), and Flt3 (1000-fold) in HUVEC cells.
Shipping	cool pack
Storage	-20°
Target names or alias	AZD2171 , NSC-732208
Molecular Weight	450, 51
Pathway	Autophagy\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Target	VEGFR\|\|\|Autophagy\|\|\|PDGFR\|\|\|c-Kit\|\|\|FLT

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Amount: 100mg

available

Delivery expected until 5/23/2024