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Linifanib

Linifanib

Manufacturer	TargetMol
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	5mg
Item no.	TMO-T2514-5mg
CASRN	796967-16-3
eClass 6.1	32169090
eClass 9.0	32169090
Available
Short Description	Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3).
Shipping	cool pack
Storage	-20°
Target names or alias	RG3635 , ABT-869 , AL-39324
Molecular Weight	375, 4
Pathway	Tyrosine Kinase/Adaptors\|\|\|Apoptosis\|\|\|Autophagy\|\|\|Angiogenesis
Target	VEGFR\|\|\|CSF-1R\|\|\|Apoptosis\|\|\|c-Kit\|\|\|FLT\|\|\|PDGFR\|\|\|Autophagy\|\|\|c-Fms

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

available

Delivery expected until 5/23/2024