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LY2811376

LY2811376

Item no.	TMO-T2639-10mM
Manufacturer	TargetMol
CASRN	1194044-20-6
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Reagents & Chemicals Molecules By Organ Breast Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	C[C@]1(CCSC(N)=N1)c1cc(c(F)cc1F)-c1cncnc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	LY2811376, LY 2811376, LY-2811376
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Beta Amyloid\|\|\|BACE\|\|\|Beta-Secretase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	320.36
Description	LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including pepsin, cathepsin D, or renin.
Pathways	Neuroscience
Formulate	C15H14F2N4S

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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