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Nutlin-3a

Nutlin-3a

Item no.	TMO-T6023-25mg
Manufacturer	TargetMol
CASRN	675576-98-4
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Lung Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	COc1ccc(C2=N[C@H]([C@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	(-)-Nutlin-3,Nutlin-3a chiral,(−)-Nutlin-3
Similar products	675576-98-4
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|Apoptosis\|\|\|E1/E2/E3 Enzyme
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	581.49
Description	Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction (Ki=90 nM) and activates p53. Nutlin-3a binds preferentially to the p53-binding pocket of MDM2, leading to stabilization of p53 and activation of the p53 pathway. Nutlin-3a has antitumor activity.
Pathways	Autophagy\|\|\|Apoptosis\|\|\|Ubiquitination

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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