PF-543

Item no.	TMO-T6085-10mg
Manufacturer	TargetMol
CASRN	1415562-82-1
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9929
Citations	1. Schnute ME, et al. Biochem J, 2012, 444(1), 79-88.
Smiles	Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Sphingosine Kinase 1 Inhibitor II,PF 543
Similar products	1415562-82-1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	S1P Receptor\|\|\|LPL Receptor\|\|\|Apoptosis\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	465.6
Description	PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 of 2.0 nM and Ki of 3.6 nM.
Pathways	GPCR/G Protein\|\|\|Apoptosis\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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