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Dorsomorphin dihydrochloride

Dorsomorphin dihydrochloride

Item no.	TMO-T6146-10mM
Manufacturer	TargetMol
CASRN	1219168-18-9
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9872
Citations	1. Zhou G, et al. J Clin Invest. 2001, 108(8), 1167-1174.
Smiles	Cl.Cl.C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Shipping Condition	Cool pack
Available
Manufacturer - Targets	AMPK\|\|\|TGF-beta/Smad\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	472.41
Description	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
Pathways	PI3K/Akt/mTOR signaling\|\|\|Stem Cells\|\|\|Autophagy\|\|\|Chromatin/Epigenetic
Bioactivity	Dorsomorphin(Ki=109 nM) is a specific, reversible, and effective AMPK inhibitor. It suppresses BMP type I receptor, but has no significant inhibition effect of several structurally related kinases including ZAPK, SYK, PKCtheta, PKA, and JAK3.
Receptor	AMPK

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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