« Back
Home /
CYC-116

CYC-116

Item no.	TMO-T6458-100mg
Manufacturer	TargetMol
CASRN	693228-63-6
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	Cc1nc(N)sc1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CYC116,CYC 116;CYC116,Aurora Kinase inhibitor
Similar products	693228-63-6
Shipping Condition	Cool pack
Available
Manufacturer - Targets	CDK\|\|\|Aurora Kinase\|\|\|VEGFR\|\|\|FLT\|\|\|S6 Kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	368.46
Description	CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.
Pathways	MAPK\|\|\|Chromatin/Epigenetic\|\|\|PI3K/Akt/mTOR signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cell Cycle/Checkpoint\|\|\|Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T6458-100mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question