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Desmethyl Erlotinib hydrochloride

Desmethyl Erlotinib hydrochloride

Item no.	TMO-T6619-10mM
Manufacturer	TargetMol
CASRN	183320-51-6
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	Cl.COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCO
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	OSI420,OSI-420,DesMethyl Erlotinib (CP-473420) HCl,CP-473420,Desmethyl Erlotinib,OSI 420
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Drug Metabolite\|\|\|EGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	415.87
Description	Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.
Pathways	JAK/STAT signaling\|\|\|Angiogenesis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Metabolism
Formulate	C21H21N3O4Â·HCl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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