HS148

Item no.	TMO-T77776-10mg
Manufacturer	TargetMol
CASRN	1892595-16-2
Amount	10 mg
Quantity options	10 mg 1 mg 25 mg 50 mg 5 mg 5 mg
Specific against	other
Smiles	O=C1N=C(SC(C(=O)N)CC)NC2=C1C=NN2C=3C=CC=C(F)C3
Alias	HS-148
Shipping Condition	Cool pack
Available
Manufacturer - Targets	DAPK
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	347, 37
Description	HS148 is a selective inhibitor of DAPK3 (death-associated protein kinase 3), with a Ki value of 119 nM. Inhibition of DAPK3 by HS148 has been shown to reduce the progression of gastric cancer by activating the ULK1-dependent pathway, which is implicated in cellular autophagy and tumor suppression mechanisms.
Pathways	Apoptosis

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