Comparison

HS148 European Partner

Item no. TMO-T77776-50mg
Manufacturer TargetMol
CASRN 1892595-16-2
Amount 50 mg
Quantity options 10 mg 1 mg 25 mg 50 mg 5 mg 5 mg
Category
Type Molecules
Specific against other
Smiles O=C1N=C(SC(C(=O)N)CC)NC2=C1C=NN2C=3C=CC=C(F)C3
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias HS-148
Shipping Condition Cool pack
Available
Manufacturer - Targets
DAPK
Shipping Temperature
Cool pack
Storage Conditions
-20°C
Molecular Weight
347, 37
Description
HS148 is a selective inhibitor of DAPK3 (death-associated protein kinase 3), with a Ki value of 119 nM. Inhibition of DAPK3 by HS148 has been shown to reduce the progression of gastric cancer by activating the ULK1-dependent pathway, which is implicated in cellular autophagy and tumor suppression mechanisms.
Pathways
Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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