Comparison

Human CD11a Monoclonal Antibody European Partner

Item no. YR0111-1mg
Manufacturer Abclonal
Amount 1 mg
Quantity options 1 mg 20 mg 5 mg
Category
Applications ELISA, FA, NT
Specific against other
Isotype IgG1 Kappa
Purity >95% Determined by SDS-PAGE
NCBI CD11a
Alias CD11A,LFA-1,LFA1A
Available
Manufacturer - Applications
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways
Manufacturer - Category
Biosimilar
Manufacturer - Conjugate / Tag
<5% Determined by SECP
Storage Conditions
2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Background
Efalizumab is a monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis.Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin.Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes. As a result efalizumab decreases cell surface expression of CD11a.
Manufacturer - Cross Reactivity
<1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Immunogen
Human CD11a
Recommended Dilution
In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Route
1×PBS pH 7.0
Manufacturer - Research Area
Cancer immunology
Gene Symbol
CD11a

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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