Fibroblast Growth Factor-4 (FGF-4), Human

Hersteller GenScript
Kategorie Produkte / Proteins
Typ Proteins
Specific against Human
Menge 100.0ug 
ArtNr Z02984-100
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Cytokines, Chemokines & Growth Factors
Description
Fibroblast Growth Factor-4 (FGF-4), also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques at GenScript, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.
M.W.
19.4kDa, observed by reducing SDS-PAGE.
Purity
> 95% by SDS-PAGE and HPLC analyses.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Specific Activity
ED50 2.0x 106 units/mg.
Storage
Lyophilized recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4C or up to 3 months at -20C.
Formulation
Lyophilized after extensive dialysis against 50mM HEPES, 750mM NaCl, pH7.5.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Sequence
Ala31-Leu206 (accession number:P08620), expressed with an N-terminal Met.
Note
For research use only
Menge: 100.0ug 
Lieferbar: In stock
Listenpreis: 266,88 €
Preis: 266,88 €
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