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FGF-4, Human Europäischer Partner

ArtNr Z02984-5
Hersteller GenScript
Menge 5 ug
Quantity options 100 ug 25 ug 5 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Purity > 95% by SDS-PAGE and HPLC analyses.
Sequence Ala31-Leu206 (accession number:P08620), expressed with an N-terminal Met.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02984_5-Fibroblast_Growth_Factor_4_FGF_4_Human,Fibroblast Growth Factor-4 (FGF-4), also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques at GenScript, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.</td></tr><tr><th>M.W.</th><td colspan="7"> 19.4kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7">> 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> <0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50 2.0× 106 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against 50mM HEPES, 750mM NaCl, pH7.5.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Ala31-Leu206 (accession number:P08620), expressed with an N-terminal Met.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products Fibroblast
Versandbedingung Gekühlt
Lieferbar
Specificity ED50 2.0x 106 units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
19.4kDa, observed by reducing SDS-PAGE.
Product Line
Growth Factors
Manufacturer - Specificity
ED50 2.0x 106 units/mg.
Description
Fibroblast Growth Factor-4 (FGF-4), also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques at GenScript, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against 50mM HEPES, 750mM NaCl, pH7.5.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Notes
For research use only

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Z02984-5-datasheet.pdf

Menge: 5 ug
Lieferbar: In stock
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