Fes

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human
Applications	WB, IHC
Protein Family	Tyrosine Kinase
Amount	100ug
Host	Rabbit
Item no.	A0612
eClass 6.1	32160702
eClass 9.0	32160702
Available
*	DESCRIPTION
Calculated MW	93kDa
Immunogen	A synthetic peptide of human FES
Gene ID	2242
Swiss Prot	P07332
Synonyms	FES; FPS; Tyrosine-protein kinase Fes/Fps; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Proto-oncogene c-Fes; Proto-oncogene c-Fps; p93c-fes;
Isotype	IgG
Purity	Affinity purification
Storage Buffer	Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
Recommended Dilutions	WB 1:500-1:1000 IHC 1:50-1:100
illustration	Western blot analysis of extracts ofrecombinantprotein, using FES antibody.

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