GAD2

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human
Applications	WB, IF, IHC
Protein Family	Neuroscience
Amount	100ug
Host	Rabbit
Item no.	A0779
eClass 6.1	32160702
eClass 9.0	32160702
Available
Calculated MW	65kDa
Immunogen	A synthetic peptide of human GAD2
Synonyms	GAD2, GAD65
Purity	Affinity purification
Storage Buffer	Store at 4C or -20C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Illustration	Western blot analysis of extracts of Jurkat celllines, using GAD2antibody.
Gene Symbol	GAD2
GeneID (Human)	2572
GeneID	2572
Protein MW	585
SWISS	Q05329
Route	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.