CYP3A4

Manufacturer	Abclonal
Type	Antibody Monoclonal
Specific against	Human
Applications	WB, IHC, ICC
Amount	100ug
Host	Mouse
Item no.	A1305
eClass 6.1	32160702
eClass 9.0	42030590
Available
Calculated MW	57kDa
Immunogen	Recombinant Protein of human CYP3A4
Synonyms	HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1
Purity	Affinity purification
Storage Buffer	Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Illustration	Western blot analysis of extracts of 293 cell line, using CYP3A4 antibody.
Gene Symbol	CYP3A4
GeneID (Human)	1576
GeneID	1576
Protein MW	503
SWISS	P08684
Route	Recombinant Protein

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Amount: 100ug

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Delivery expected until 7/2/2024