BGLAP

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human
Applications	WB, IHC
Amount	100ug
Host	Rabbit
Item no.	A1530
eClass 6.1	32160702
eClass 9.0	32160702
Available
Calculated MW	11kDa
Immunogen	A synthetic peptide of human BGLAP
Synonyms	BGLAP, Osteocalcin, Bone Gla protein, Gamma-carboxyglutamicacid-containing protein
Purity	Affinity purification
Storage Buffer	Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	Bone g-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. In addition, osteocalcin is one of the most abundant, non-collagenous proteins found in mineralized adult bone. Genetic variation at the osteocalcin locus on chromosome 1q impacts postmenopause bone mineral density (BMD) levels and may predispose some women to osteoporosis.
Illustration	Western blot analysis of extracts of 293cell line, using BGLAP antibody.
Gene Symbol	BGLAP
GeneID (Human)	632
GeneID	632
Protein MW	100
SWISS	P02818
Route	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 100ug

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Delivery expected until 7/2/2024