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Anti-Growth Hormone/GH1 Antibody Picoband®

Anti-Growth Hormone/GH1 Antibody Picoband®

Item no.	BOS-RP1007-FITC
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Metabolism Diabetes Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, IHC, ELISA
Specific against	Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	FITC
Sensitivity	>5000 cells
Sequence	Belongs to the heparin-binding growth factors family.
Citations	1. Niall, H. D.; Hogan, M. L.; Sauer, R.; Rosenblum, I. Y.; Greenwood, F. C. : Sequence of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication. Proc. Nat. Acad. Sci. 68: 866-869, 1971. 2. Sundstrom, M.; Lundqvist, T.; Rodin, J.; Giebel, L. B.; Milligan, D.; Norstedt, G. : Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 angstrom resolution. J. Biol. Chem. 271: 32197-32203, 1996.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Somatotropin,Growth hormone,Gh1,Gh
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	22 kDa
Calculated Molecular weight	24656 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Rat ELISA, 0.1-0.5μg/ml
Gene Name	GH1
Gene Full Name	Somatotropin
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Growth Hormone (GH) is mapped to 17q22-q24. Human growth hormone has a molecular mass of 22, 005 and contains 191 amino acid residues with 2 disulfide bridges. Rat GH shares 98% amino acid sequence homology with mouse. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.
Immunogen	E. coli-derived rat GH recombinant protein (Position: F27-F216).
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Developmental Biology, Growth Factors/Hormones, Signal Transduction
Protein Name	Somatotropin
Protein Function	Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Subcellular Localization	Secreted.
Description	Boster Bio Anti-Growth Hormone/GH1 Antibody catalog # RP1007. Tested in ELISA, IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue.
Sequence Similarities	Belongs to the heparin-binding growth factors family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-RP1007-FITC-datasheet.pdf

BOS-RP1007-FITC-safety-datasheet.pdf