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RUNX1T1 Peptide (AAP33996)

RUNX1T1 Peptide (AAP33996)

Manufacturer	AVIVA Systems Biology
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Epigenetics Neural Development Peptides & Proteins Western Blot Peptides By Organ Heart & Blood Cancer Cytoskeleton Markers
Type	Peptides
Specific against	other
Format	Lyophilized powder
Applications	WB
Amount	100 ug
Item no.	AAP33996
eClass 6.1	34160400
eClass 9.0	32160409
Available
Description	This is a synthetic peptide designed for use in combination with anti-RUNX1T1 antibody (Catalog #: ARP33996_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	RUNX1T1
Protein size	567
Molecular weight	62kDa
Product format	Lyophilized powder
Gene id	862
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	CBFA2T2, HDAC1, HDAC3, NCOR1, SIN3A, TCF12, TCF12, TCF3, TCF4, ABI3, ATN1, BCL6, C19orf57, CBFA2T3, GFI1, HDAC1, HDAC3, HDAC8, HSP90AA1, ID1, ID3, KPNA1, KPNB1, NCOR1, NCOR2, NECAB2, PRKAR2A, RUNX1T1, SIN3A, TAF9B, TCF3, TCF4, UBQLN4, WBP11, ZBTB16, ABI3, C19orf57, CBFA2T2, CBFA2T3, CEP170L, GFI1, HDAC1, HDAC2, HDAC3, HDAC8, KPNA1, KPNB1, NCOR1, NCOR2, NECAB2, OTUD4, PRKAR2A, RUNX1T1, SIN3A, TAF9B, THRAP3, VDR, WBP11, ZBTB16
Description of target	RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8; 21)(q22; q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

available

Delivery expected until 6/13/2024