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NAGPA Peptide - N-terminal region (AAP47241)

NAGPA Peptide - N-terminal region (AAP47241)

Manufacturer	AVIVA Systems Biology
Category	Peptides & Proteins Western Blot Peptides
Type	Peptides
Specific against	Human
Format	Lyophilized powder
Applications	WB
Amount	100ug
Item no.	AAP47241
eClass 6.1	34160400
eClass 9.0	32160409
Available
Description	This is a synthetic peptide designed for use in combination with anti-NAGPA Antibody (ARP47241_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	NAGPA
Protein size	515
Molecular weight	53kDa
Product format	Lyophilized powder
Gene id	51172
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

available

Delivery expected until 5/30/2024