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Anti-CEA Antibody (Center)

Anti-CEA Antibody (Center)

Item no.	BOS-A00356-1-80ul
Manufacturer	Boster
Amount	80 ul
Quantity options	400 ul 80 ul
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Immunohistochemistry Western Blot By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Testicular & Prostate Cancer Gallbladder Cancer Gastric Cancer Pancreatic Cancer Thyroid Cancer
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Alias	Carcinoembryonic antigen-related cell adhesion molecule 5,Carcinoembryonic antigen,CEA,Meconium antigen 100,CD66e,CEACAM5,CEA
Available
Manufacturer - Applications	IHC-P-Leica, Flow Cytometry, WB
Manufacturer - Category	Primary Antibodies
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	76796 Da
Clonality	Polyclonal
Application Details	WB: 1:1000 IHC-P-Leica: 1:500 FC: 1:10-1:50
Gene Name	CEACAM5
Background	CEA is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. It is a receptor for E.coli Dr adhesins.
Immunogen	This CEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human CEA.
Contents	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Manufacturer - Research Category	Cancer, Immunology, Microbiology, Signal Transduction
Protein Function	Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).
Subcellular Localization	Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface Note=Localized to the apical glycocalyx surface
Description	Boster Bio Anti-CEA Antibody (Center) (Catalog # A00356-1). Tested in IHC-P-Leica, Flow Cytometry, WB application(s). This antibody reacts with Human.
Tissue Specificity	Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A00356-1-80ul-datasheet.pdf

BOS-A00356-1-80ul-safety-datasheet.pdf