SQSTM1 Antibody

SQSTM1

A170 antibody; DMRV antibody; EBI 3 associated protein of 60 kDa antibody; EBI 3 associated protein p60 antibody; EBI3 associated protein of 60 kDa antibody; EBI3 associated protein p60 antibody; EBI3-associated protein of 60 kDa antibody; EBIAP antibody; FTDALS3 antibody; MGC127197 antibody; ORCA antibody; OSF-6 antibody; Osi antibody; OSIL antibody; Oxidative stress induced like antibody; p60 antibody; p62 antibody; p62B antibody; Paget disease of bone 3 antibody; PDB 3 antibody; PDB3 antibody; Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa antibody; Phosphotyrosine independent ligand for the Lck SH2 domain p62 antibody; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa antibody; PKC-zeta-interacting protein antibody; Protein kinase C-zeta-interacting protein antibody; Sequestosome 1 antibody; Sequestosome-1 antibody; SQSTM 1 antibody; SQSTM_HUMAN antibody; Sqstm1 antibody; STAP antibody; STONE14 antibody; Ubiquitin binding protein p62 antibody; Ubiquitin-binding protein p62 antibody; ZIP 3 antibody; ZIP antibody; ZIP3 antibody

Recombinant Human Sequestosome-1 protein (16-310AA)

Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

>95%, Protein G purified

Signal Transduction

Recombinant Human Sequestosome-1 protein (16-310AA)