Recombinant Human Fibroblast growth factor receptor-like 1(FGFRL1),partial (Active)

Cytokine / Growth Factor

39.9 kDa

Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.

Membrane, Single-pass type I membrane protein

FGFRL1

Lyophilized from a 0.2 um filtered 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Extracellular Domain