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Recombinant Human Metalloreductase STEAP2(STEAP2)

Recombinant Human Metalloreductase STEAP2(STEAP2)

Manufacturer	Cusabio
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Development Peptides & Proteins Recombinant Proteins By Organ Testicular & Prostate Cancer
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	10ug
Item no.	CSB-CF854119HU-10
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research Topic	Cancer
Uniprot ID	Q8NFT2
Gene Names	STEAP2
Organism	Homo sapiens (Human)
AA Sequence	MESISMMGSPKSLSETFLPNGINGIKDARKVTVGV IGSGDFAKSLTIRLIRCGYHVVIGSRNPKFASEFF PHVVDVTHHEDALTKTNIIFVAIHREHYTSLWDLR HLLVGKILIDVSNNMRINQYPESNAEYLASLFPDS LIVKGFNVVSAWALQLGPKDASRQVYICSNNIQAR QQVIELARQLNFIPIDLGSLSSAREIENLPLRLFT LWRGPVVVAISLATFFFLYSFVRDVIHPYARNQQS DFYKIPIEIVNKTLPIVAITLLSLVYLAGLLAAAY QLYYGTKYRRFPPWLETWLQCRKQLGLLSFFFAMV HVAYSLCLPMRRSERYLFLNMAYQQVHANIENSWN EEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNA LNWREFSFIQSTLGYVALLISTFHVLIYGWKRAFE EEYYRFYTPPNFVLALVLPSIVILGKIILFLPCIS RKLKRIKKGWEKSQFLEEGMGGTIPHVSPERVTVM
Expression Region	1-490aa
Sequence Info	Full Length
Source	in vitro E.coli expression system
Tag Info	N-terminal 10xHis-SUMO-tagged
MW	74.6 kDa
Alternative Name(s)	Prostate cancer-associated protein 1 Protein up-regulated in metastatic prostate cancer
Relevance	Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor
Reference	"Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells." Vaghjiani R.J., Talma S., Murphy C.L. Tissue Eng Part A 15:2073-2083(2009)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Subcellular Location	Endosome membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein
Protein Families	STEAP family
Tissue Specificity	Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.
Tag Information	N-terminal 10xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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