Comparison

Recombinant Human Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial(IDH3G)

Manufacturer Cusabio
Category
Type Proteins
Specific against other
Amount 10ug
Host E.coli
Item no. CSB-EP010993HU-10
eClass 6.1 34160400
eClass 9.0 42020190
Available
Research Topic
Signal Transduction
Uniprot ID
P51553
Gene Names
IDH3G
Organism
Homo sapiens (Human)
AA Sequence
FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVK SVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRR NRVALKGNIETNHNLPPSHKSRNNILRTSLDLYAN VIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEH ESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRK KVTAVHKANIMKLGDGLFLQCCREVAARYPQITFE NMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVC AGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLA SMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGR AVEA
Expression Region
40-393aa
Sequence Info
Full Length of Mature Protein
Source
E.coli
Tag Info
N-terminal 6xHis-SUMO-tagged
MW
54.8 kDa
Alternative Name
Isocitric dehydrogenase subunit gammaNAD(+)-specific ICDH subunit gamma
Reference
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular Location
Mitochondrion
Protein Families
Isocitrate and isopropylmalate dehydrogenases family
Amount: 10ug
Available: In stock
Listprice: €175.45
Price: €175.45
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