Comparison

Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2(GABARAPL2)

Manufacturer Cusabio
Category
Type Proteins
Specific against other
Amount 200ug
Host E.coli
Item no. CSB-RP034844h-200
Eclass 6.1 34160400
Eclass 9.0 42020190
Available
Alternative Name(s)
GABA(A) receptor-associated protein-like 2Ganglioside expression factor 2 ; GEF-2General protein transport factor p16Golgi-associated ATPase enhancer of 16 kDa ; GATE-16MAP1 light chain 3-related protein
AA Sequence
MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEK VSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQL PSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFL YVAYSGENTFGF
Research Topic
Transport
Uniprot ID
P60520
Gene Names
GABARAPL2
Tag Info
N-terminal GST-tagged
Expression Region
1-117aa
MW of Fusion Proten
40, 7
Sequence Info
Full Length
Relevance
Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 . Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirents and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore mbrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Reference
Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain possible role of vesicular transport in axonal elongation.Okazaki N., Yan J., Yuasa S., Ueno T., Kominami E., Masuho Y., Koga H., Muramatsu M.-A.Brain Res. Mol. Brain Res. 85:1-12(2000)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Species
Homo sapiens (Human)
Amount: 200ug
Available: In stock
Listprice: €546.07
Price: €546.07
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