« Back
Home /
CRT0066854

CRT0066854

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	100mg
Item no.	HY-18713-100mg
CASRN	1438881-19-6
Available
Product Description	CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	COVID-19-anti-virus
Formula	C24H25N5S
References	[1].Kjær S, et al. Adenosine-binding motif mimicry and cellular effects of a thieno[2, 3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes. Biochem J. 2013 Apr 15; 451(2):329-42.
MolecularWeight	415.55
Research Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 50 mg/mL (120.32 mM; Need ultrasonic)
Target	PKC; ROCK
Isoform	PKCζ; ROCK2
Pathway	Epigenetics; TGF-beta/Smad; Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100mg

available

Delivery expected until 4/13/2023

Compare

Add to wishlist

Recommend by mail

Request delivery time

Ask a technical question